Research Interests
Our research addresses relevant biological questions involving molecular recognition, protein folding and stability. We are currently studying the role of cytosolic human thioredoxin in cancer cells, the structural biology of immunologically active protein fragments, the electrostatic contributions to protein stability, the mechanism of oligomerization, and natively unstructured proteins. Our approach is interdisciplinary and involves:
- The use of complementary tools from molecular and cell biology, microbiology, protein chemistry, biochemistry, and biophysics.
- Calorimetry and spectroscopies such as fluorescence, circular dichroism, and nuclear magnetic resonance constitute the backbone of our
biophysical studies of proteins and protein fragments.
- Fall 2006, General Chemistry
- Fall 2005, Molecular Biophysics
- Spring 2003 Physical Biochemistry
- Spring 2004 Minicourse on Protein (Mis)Function in Diseases
- Fall 2002 General Chemistry I
- Favorite NYC site: channel 25